ive seen grayanotoxin written like 50 different ways on here and half of them sound made up. can someone explain what it actually IS in normal words? not a wikipedia paste, just what is the thing doing
short version: its a plant compound (a diterpenoid) the rhododendron makes, ends up in the nectar, bees bring it in. not added, not mixed in by anyone. just in the flower
@Jules and the plant isnt making it for us lol. its a defence chemical for the rhododendron. honey just catches it as a side effect of which flowers the bees worked
the bit that matters for what people feel: it binds to voltage-gated sodium channels and keeps them open longer than they should be. thats a nerve/muscle thing. im not your clinician and im not touching amounts, but mechanistically thats the whole story, it interferes with how nerves switch off
@DocOnTheSide ok that helps. so the lightheaded/heavy stuff is just nerve signalling being messed with, not some mystical honey energy