I've been using mad honey specifically for sleep difficulties for about 3 months, consistently enough to have something worth reporting.
Dosage: 1/2 to 1 tsp, 45–60 min before I want to be asleep. 2–3x per week, not every night — I noticed tolerance building by day 4 of consecutive use. Source: same seller for 10+ months with consistent CoAs.
What I've found: it shortens the time it takes me to fall asleep and I wake up less during the night. The effect is mild, not dramatically sedative. More like the difference between lying in bed tense and lying in bed genuinely relaxed.
What I've noticed waning: if I use it more than 3 nights in a row the effect gets noticeably weaker. Taking 2 nights off resets it almost completely.
What I can't claim: whether this is sustainable long-term, whether it's doing anything I'd call "treating" insomnia, or whether the same would work for anyone else. This is just my log.
The tolerance observation is consistent with what we'd expect from repeated sodium channel modulation — tachyphylaxis (short-term tolerance) is a known phenomenon with grayanotoxin.
Your spacing approach (every other night at most) is consistent with the pharmacology. Tachyphylaxis with grayanotoxin is real and faster than most people expect — the 2-nights-off reset you describe is also consistent with how sodium channel sensitivity recovers once the compound clears.
One thing worth tracking over time: note whether the effective dose stays stable or gradually drifts upward. If you find yourself needing more to achieve the same result over months, that's worth paying attention to.
Similar experience here over about 5 months. The tolerance point is important and worth repeating: using it every night stops it working well within a week. The magic is in the spacing.
I keep a simple log — date, dose, time taken, rough time to sleep, quality rating, any notes. Made it much easier to spot the tolerance pattern once I could see it laid out. The every-other-night ceiling became obvious in the data before I'd consciously noticed it from feel alone. Highly recommend logging if you're using this regularly for anything specific.